Study of Protein Carbonyl Group, Nitric Oxide and Mda (index of Lipid Peroxidation) as Biomarkers of Oxidative Stress in Type 2 Diabetes Mellitus

نویسندگان

  • Vilas U Chavan
  • R R Melinkeri
  • Vilas U. Chavan
چکیده

Conclusion: Biomarkers of oxidative stress such as protein carbonyl, NOx (total nitrites) and MDA are significantly increased in type 2 DM compared to healthy subjects. There is increased protein oxidation, lipid peroxidation, and increased conversion of NO. to its end products like nitrite and nitrates in type 2 DM. This suggests that there is increased production of reactive oxygen species (ROS) and oxidative stress in type 2 DM patients compared to healthy subjects.

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تاریخ انتشار 2013